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Mutations in K-ras and Epidermal Growth Factor Receptor Expression in Korean Patients With Stages III and IV Colorectal Cancer

✍ Scribed by Lee, W.-S.; Jeong Heum Baek, ; Jung Nam Lee, ; Woon Kee Lee,

Book ID
119968004
Publisher
SAGE Publications
Year
2011
Tongue
English
Weight
314 KB
Volume
19
Category
Article
ISSN
1066-8969

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## Abstract Mutations of the __KRAS__, __BRAF__, and __PIK3CA__ genes have been reported in colorectal cancer (CRC), associated with resistance to epidermal growth factor receptor (EGFR)‐targeted monoclonal antibody therapy. These reports have mainly emanated from Western countries, however, and li