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Mutations in holoprosencephaly

✍ Scribed by Deeann Wallis; Maximilian Muenke


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
270 KB
Volume
16
Category
Article
ISSN
1059-7794

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## Abstract Holoprosencephaly (HPE) is the most common developmental defect of the forebrain and midface in humans, with a frequency of 1/16,000 live births. Different genes are implicated in the pathogenesis of HPE; these include __SHH, ZIC2, SIX3, TGIF__, and human __DKK1__. We describe here a fa

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