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Mutations in FOXC2 are strongly associated with primary valve failure in veins of the lower limb

✍ Scribed by Mellor, R.H.; Brice, G.; Stanton, A.W.B.


Book ID
122123316
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
34 KB
Volume
46
Category
Article
ISSN
1097-6809

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## Abstract A series of 121 human breast tumors was screened for point mutations in exons 5 through 8 of the p53 gene, by SSCP analysis. On the same tumor samples, the S‐phase index (SPI) was determined by the incorporation of BUdR in fresh tissue. p53 mutations were observed in 29% of the cases. T