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Mutations in Exons 9 and 13 of KIT Gene Are Rare Events in Gastrointestinal Stromal Tumors: A Study of 200 Cases

✍ Scribed by Jerzy Lasota; Agnieszka Wozniak; Maarit Sarlomo-Rikala; Janusz Rys; Radzislaw Kordek; Aziza Nassar; Leslie H. Sobin; Markku Miettinen


Book ID
117022296
Publisher
American Society for Investigative Pathology
Year
2000
Tongue
English
Weight
981 KB
Volume
157
Category
Article
ISSN
0002-9440

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## Abstract Gastrointestinal stromal tumors are mesenchymal tumors arising in the stomach and small bowel and more rarely in the rectum, esophagus, peritoneum and retroperitoneum. These tumors are characterized by __KIT__ or __PDGFRA__ mutations. __KIT__ mutations are all in frame and lead to const