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Mutations in DNA damage response genes and breast cancer susceptibility

✍ Scribed by Robert B Clarke


Book ID
120701044
Publisher
BioMed Central
Year
2002
Tongue
English
Weight
35 KB
Volume
4
Category
Article
ISSN
1465-5411

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## Abstract Cigarette smoking is the major risk factor for lung cancer, and together with alcohol for head and neck (Hο£ΏN) cancer. These genotoxics produced DNA damage and particularly double‐strand breaks (DSB) that are removed by various repair pathways. To understand the initiation of these cance