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Mutations in 23S rRNA gene associated with decreased susceptibility to tiamulin and valnemulin in Mycoplasma gallisepticum

✍ Scribed by Bei-Bei Li; Jian-Zhong Shen; Xing-Yuan Cao; Yang Wang; Lei Dai; Si-Yang Huang; Cong-Ming Wu


Book ID
109331975
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
95 KB
Volume
308
Category
Article
ISSN
0378-1097

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## Abstract The DNA repair enzyme O^6^‐methylguanine‐DNA methyltransferase (MGMT) removes alkylating adducts from the O^6^ position of guanine and protects cells from cytotoxic and mutagenic effects. Expression of __MGMT__ is decreased in some cancers, which may be the result of methylation of CpG