Mutations associated with hemophilia B in Turkish patients
✍ Scribed by S. Hande Çaǧlayan; Yeşim Gökmen; Gülten Aktuǧlu; Aytemiz Gürgey; Steve S. Sommer
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 102 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1059-7794
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An 11-year-old boy with mild hemophilia A was admitted to our hospital because of focal convulsions. Magnetic resonance imaging showed an old occipital infarct. Protein C, S, antithrombin III, anticardiolipin antibodies and fibrinogen were normal. Heterozygosity for factor V Leiden mutation was dete
## Communicated by Francesco Giannelli Exogenous (e.g., environmental) mutagens produce characteristic patterns of mutation. In contrast, endogenous mutation processes likely are associated with an invariant pattern of mutation. Analysis of factor IX gene mutations among large samples of hemophili