𝔖 Bobbio Scriptorium
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Mutational Specificity in Bacteria

✍ Scribed by Miller, J H


Book ID
120165498
Publisher
Annual Reviews
Year
1983
Tongue
English
Weight
822 KB
Volume
17
Category
Article
ISSN
0066-4197

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Mutational specificity describes the composite of all of the genetic alterations in a collection of mutations arising from a specific treatment. The information includes not only the nature of the genetic change (e.g., a base substitution or a frameshift), but also information about nucleotide posit

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Tamoxifen, an important drug in breast cancer treatment, causes liver cancer in rats. The standard range of in vitro tests have failed to show that it causes DNA damage, but 32P-postlabelling and DNA-binding studies have shown that tamoxifen forms DNA adducts in rat liver. In 1995 a transgenic rat (