✦ LIBER ✦

Mutational patterns in the frameshift-regulating site of HIV-1 selected by protease inhibitors

✍ Scribed by Elena Knops; Léa Brakier-Gingras; Eugen Schülter; Herbert Pfister; Rolf Kaiser; Jens Verheyen

Book ID: 111657413
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 339 KB
Volume: 201
Category: Article
ISSN: 0300-8584
DOI: 10.1007/s00430-011-0224-z

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Diverse pattern of protease inhibitor re

Diverse pattern of protease inhibitor resistance mutations in HIV-1 infected patients failing nelfinavir

✍ Veronica Svedhem; A. Lindkvist; T. Bergroth; Lidman Knut; A. Sönnerborg 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB

## Abstract The aim of the study was to describe the pattern of resistance mutations in human immunodeficiency virus type 1 (HIV‐1) infected patients experiencing their first protease inhibitor (PI) failure on nelfinavir (NFV)‐containing therapy. Earlier PI‐naïve patients (n = 172) with NFV‐contain

Comparing the Accumulation of Active- an

Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease †

✍ Clemente, José C.; Moose, Rebecca E.; Hemrajani, Reena; Whitford, Lisa R. S.; Go 📂 Article 📅 2004 🏛 American Chemical Society 🌐 English ⚖ 753 KB

A Priori Prediction of Activity for HIV-

A Priori Prediction of Activity for HIV-1 Protease Inhibitors Employing Energy Minimization in the Active Site

✍ Holloway, M. Katharine; Wai, Jenny M.; Halgren, Thomas A.; Fitzgerald, Paula M. 📂 Article 📅 1996 🏛 American Chemical Society 🌐 English ⚖ 17 KB

Characterization of human immunodeficien

Characterization of human immunodeficiency virus type 1 (HIV-1) containing mutations in the nucleocapsid protein at a putative HIV-1 protease cleavage site

✍ James A. Thomas; Sergey Shulenin; Lori V. Coren; William J. Bosche; Tracy D. Gag 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 350 KB

HIV-1 Protease Mutations and Inhibitor M

HIV-1 Protease Mutations and Inhibitor Modifications Monitored on a Series of Complexes. Structural Basis for the Effect of the A71V Mutation on the Active Site †

✍ Skálová, Tereza; Dohnálek, Jan; Dušková, Jarmila; Petroková, Hana; Hradílek, Mar 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 464 KB

Thermodynamic rules for the design of hi

Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets

✍ Hiroyasu Ohtaka; Salman Muzammil; Arne Schön; Adrian Velazquez-Campoy; Sonia Veg 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 237 KB