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Mutational analysis of theWASPgene in 2 Korean families with Wiskott-Aldrich syndrome

✍ Scribed by Eun-Kyeong Jo; Takeshi Futatani; Hirokazu Kanegane; Takeo Kubota; Young-Ho Lee; Jin-A Jung; Chang-Hwa Song; Jeong-Kyu Park; Shigeaki Nonoyama; Toshio Miyawaki


Publisher
Carden Jennings Publishing
Year
2003
Tongue
English
Weight
542 KB
Volume
78
Category
Article
ISSN
0925-5710

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The Wiskott-Aldrich Syndrome (WAS) is an X-linked recessive immunodeficiency caused by mutation in the gene encoding WAS protein (WASP). The disease is characterized by eczema, thrombocytopenia and severe immunodeificency and is associated with extensive clinical heterogeneity. Mutation studies indi