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Mutational analysis of Escherichia coli PepA, a multifunctional DNA-binding aminopeptidase

✍ Scribed by Daniel Charlier; Abdelaziz Kholti; Nadine Huysveld; Daniel Gigot; Dominique Maes; Thia-Lin Thia-Toong; Nicolas Glansdorff


Book ID
115630506
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
944 KB
Volume
302
Category
Article
ISSN
0022-2836

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NAD(+)-dependent DNA ligases are essential enzymes in bacteria, with the most widely studied of this class of enzymes being LigA from Escherichia coli. NAD(+)-dependent DNA ligases comprise several discrete structural domains, including a BRCT domain at the C-terminus that is highly-conserved in thi