The tumor suppressor gene CDKN2 (p16/MTS1) resides on chromosome 9p21 and encodes a 16 kDa inhibitor of the cyclin-dependent kinases. Inactivation of CDKN2 by homozygous deletion, point mutation, and recently described aberrant methylation in the 5' promoter region may increase progression through t
Mutational Analysis of CDKN2 (CDK4I/MTS1) Gene in Tissues and Cell Lines of Human Prostate Cancer
β Scribed by Komiya, Akira ;Suzuki, Hiroyoshi ;Aida, Sara ;Yatani, Ryuichi ;Shimazaki, Jun
- Book ID
- 108580989
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1995
- Tongue
- English
- Weight
- 229 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0910-5050
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