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Mutational activation of BRAF is not a major event in sporadic childhood papillary thyroid carcinoma

✍ Scribed by Rosenbaum, Eli; Hosler, Gregory; Zahurak, Marianna; Cohen, Yoram; Sidransky, David; Westra, William H

Book ID
109888097
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
138 KB
Volume
18
Category
Article
ISSN
0893-3952

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## Abstract ## BACKGROUND: Although several studies undoubtedly demonstrated that __BRAF__ mutation is an important genetic event in the pathogenesis of papillary thyroid carcinoma (PTC), its prognostic significance and correlation with less differentiated states remains unclear. It has been sugge