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Mutation watch: Mouse brachyury (T), the T-box gene family, and human disease

โœ Scribed by Miriam H. Meisler


Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
920 KB
Volume
8
Category
Article
ISSN
0938-8990

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The T-box gene family
โœ Virginia E. Papaioannou; Lee M. Silver ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 142 KB

A novel family of transcription factors that appears to play a critical role in the development of all animal species was recently uncovered on the basis of homology to the DNA binding domain of the Brachyury, or T locus, gene product. Phylogenetic studies have shown the ancient origin of this gene