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Mutation spectra induced by replication of two vicinal oxidative DNA lesions in mammalian cells

โœ Scribed by A. Gentil; F. Le Page; J. Cadet; A. Sarasin

Book ID
114070203
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
135 KB
Volume
452
Category
Article
ISSN
0027-5107

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Quinone-induced cell death is often attributed to oxidative stress during which the formation of DNA strand breaks is thought to play an important role. In this study, extensive DNA damage was observed in human chronic myelogenous leukemic cells (K562) exposed for 15 minutes to low concentrations (1