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Mutation screening of the ARX gene in patients with autism

✍ Scribed by Pauline Chaste; Gudrun Nygren; Henrik Anckarsäter; Maria Råstam; Mary Coleman; Marion Leboyer; Christopher Gillberg; Catalina Betancur


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
57 KB
Volume
144B
Category
Article
ISSN
1552-4841

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## Abstract ## BACKGROUND The retinoic acid (RA)–catabolizing enzyme Cyp26a1 plays an important role in protecting tailbud tissues from inappropriate exposure to RA. __Cyp26a1__‐null animals exhibit caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestiv