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Mutation screening for the 5α-reductase type 2 gene in Japanese men with idiopathic azoospermia

✍ Scribed by Keiichi Itoh; Isoji Sasagawa; Yasuhiro Suzuki; Junko Ashida; Teruhiro Nakada; Tsutomu Ogata


Book ID
119418573
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
52 KB
Volume
77
Category
Article
ISSN
1556-5653

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Male pseudohermaphroditism caused by steroid 5␣-reductase deficiency is an autosomal recessive disorder. The enzyme steroid 5␣-reductase 2 (encoded by the SRD5A2 gene) catalyses the conversion of testosterone to dihydrotestosterone, which is required for normal differentiation of the external male g