Mutation rate estimate in hereditary cutaneous malignant melanoma/dysplastic nevi

Abnormal sensitivity to UV-radiation in

Abnormal sensitivity to UV-radiation in cultured skin ibroblasts from patients with hereditary cutaneous malignant melanoma and dysplastic nevus syndrome

✍ Paul J. Smith; Mark H. Greene; Deborah A. Devlin; Elisabeth A. McKeen; Malcolm C 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 French ⚖ 650 KB

## Abstract The dysplastic nevus syndrome (DNS) is a preneoplastic melanocyte abnormality which occurs in families affected by hereditary cutaneous malignant melanoma (HCMM). Although environmental exposures, especially solar UV‐irradiation, have been implicated as risk factors in sporadic melanoma