✦ LIBER ✦

Mutation of BRAF is uncommon in AML FAB type M1 and M2

✍ Scribed by Smith, M L; Snaddon, J; Neat, M; Cambal-Parrales, M; Arch, R; Lister, T A; Fitzgibbon, J

Book ID: 110055343
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 71 KB
Volume: 17
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2402787

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mutations of the AML1 gene in acute myel

Mutations of the AML1 gene in acute myeloid leukemia of FAB types M0 and M7

✍ Stephen E. Langabeer; Rosemary E. Gale; Sara J. Rollinson; Gareth J. Morgan; Dav 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 260 KB

## Abstract The __AML1__ gene encodes a transcription factor that, together with its heterodimeric partner CBFB, regulates a number of target genes that are essential for normal hemopoiesis. In acute myeloid leukemia (AML), __AML1__ is disrupted not only by chromosomal translocations but also by mu

Mutations of CEBPA in acute myeloid leuk

Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2

✍ Jennifer Snaddon; Matthew L. Smith; Michael Neat; Maxine Cambal-Parrales; Amanda 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 445 KB

CEBPA encodes the transcription factor C/EBPalpha and is specifically up-regulated during granulocytic differentiation. The gene is mutated in approximately 20% of patients with acute myeloid leukemia (AML) FAB type M2 and occurs in the absence of the t(8;21). In much the same way as specific transl

DR negativity is a distinctive feature o

DR negativity is a distinctive feature of M1/M2 AML cases with NPM1 mutation

✍ Meilani Syampurnawati; Eiji Tatsumi; Bambang Ardianto; Mariko Takenokuchi; Yuji 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 92 KB

FAB and chemical ionization in the produ

FAB and chemical ionization in the production of [M+ H]+ and [M− H]− species from 2-aryl-2-methyl-1,3-dithianes

✍ Alberto Sturaro; Pietro Traldi; Cristina Paradisi 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 428 KB

The unimolecular fragmentations of [M + HI+ and [M -HI-ions from four 2-aryl-Zmethyl-1,3-dithianes are described and clarified with the aid of deuterated derivatives. Comparison of the MIKE spectra of [M + HI+ species obtained under chemical ionization and fast atom bombardment (FAB) conditions reve

Mutations in ALMS1 cause obesity, type 2

Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndrome

✍ Collin, Gayle B.; Marshall, Jan D.; Ikeda, Akihiro; So, W. Venus; Russell-Eggitt 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 592 KB

AML1-ETO9a is correlated with C-KIT over

AML1-ETO9a is correlated with C-KIT overexpression/mutations and indicates poor disease outcome in t(8;21) acute myeloid leukemia-M2

✍ Jiao, B; Wu, C-F; Liang, Y; Chen, H-M; Xiong, S-M; Chen, B; Shi, J-Y; Wang, Y-Y; 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 256 KB