BRCA1 is a tumour suppressor gene located on chromosome band 17q21. It is estimated that mutations in the BRCA1 gene account for approximately 45% of the breast cancer families and almost all of the breast/ovarian cancer families. We have used single strand conformation polymorphism analysis, direct
Mutation in the coding region of the BRCA1 gene leads to aberrant splicing of the transcript
โ Scribed by Hilmi Ozcelik; Raluca Nedelcu; Vivian W.Y. Chan; Xiu-Hong Shi; Joan Murphy; Barry Rosen; Irene L. Andrulis
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 119 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1059-7794
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