Genotype-phenotype correlation between p
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Yvonne L. Wallis; Fiona Macdonald; Maj Hultรฉn; Jenny E. V. Morton; Carol M. McKe
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Article
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1994
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Springer
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English
โ 668 KB
Mutations in the adenomatous polyposis coli (APC) gene are responsible for the disease familial adenomatous polyposis (FAP), a dominantly inherited predisposition to colorectal cancer. The most common extra-colonic manifestation is congenital hypertrophy of the retinal pigment epithelium (CHRPE), ex