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Mutation and expression of the p51/p63 gene in human colorectal carcinoma

✍ Scribed by Koyama, Toru; Hamada, Kunihiro; Shimizu, Kimihiro; Yokota, Jun; Ohwada, Susumu; Morishita, Yasuo


Book ID
122739480
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
186 KB
Volume
118
Category
Article
ISSN
0016-5085

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Frequent gain of the p40/p51/p63 gene lo
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We have identified a new human p53 homologue, p40 (p51/p63). This gene was mapped to the distal arm of 3q and was found to be essential for normal epithelial development. We used microsatellite and FISH analyses to search for genetic alterations of p40 in primary HNSCC. A more precise localization o