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Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas

✍ Scribed by Fransen, K.


Book ID
125331366
Publisher
Oxford University Press
Year
2003
Tongue
English
Weight
148 KB
Volume
25
Category
Article
ISSN
0143-3334

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## Abstract Gene mutations in __APC__, __K‐ras__, and __p53__ are thought to be essential events for colorectal cancer development. Recent data seem to indicate that __K‐ras__ and __p53__ mutations rarely co‐exist in the same tumor, indicating that these alterations do not represent a synergistic e