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Mutation analysis of mitotic checkpoint genes (hBUB1 and hBUBR1) and microsatellite instability in adult T-cell leukemia/lymphoma

✍ Scribed by Koichi Ohshima; Seiji Haraoka; Shingo Yoshioka; Makoto Hamasaki; Takehiro Fujiki; Junji Suzumiya; Chika Kawasaki; Motonobu Kanda; Masahiro Kikuchi


Book ID
117466612
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
173 KB
Volume
158
Category
Article
ISSN
0304-3835

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## Abstract We studied rearrangement of human T cell receptor genes (TCR) of CΞ², CΞ³, VΞ³ and JΞ³ in 34 cases of adult T cell leukemia/lymphoma (ATLL), consisting of 29 cases with monoclonally integrated HTLV‐I proviral DNA (ATLL‐W) and five without monoclonal integration (ATLL‐O), in comparison with