Mutation analysis of hepatitis B virus promoters in chronically infected children
โ Scribed by J. W. Sohn; C. W. Lee; J. H. Lee; K. C. Lee; C. S. Son; J. W. Lee; Y. M. Ha-Lee
- Book ID
- 106210399
- Publisher
- Springer Vienna
- Year
- 2005
- Tongue
- English
- Weight
- 236 KB
- Volume
- 150
- Category
- Article
- ISSN
- 1432-8798
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
It is well established that during lamivudine treatment, mutations emerge within the polymerase gene but there is little information about the selection of other mutations in the whole hepatitis B virus (HBV) genome. The aim of this study was to investigate whether mutations outside this region are
The core promoter region of hepatitis B virus genomes regulates transcription of the precore and pregenomic mRNAs encoding hepatitis B e antigen (HBeAg) and core antigen that contain target epitopes for cytotoxic T lymphocytes. The prevalence and clinical significance of mutations in this region wer
In a previous study a partial inhibition of viral replication was observed in HBeAg-positive patients after acyclovir (ACV) treatment. To assess those results and to evaluate different treatment regimens, a randomized controlled trial with ACV given at 45 mg/kg/day by continuous infusion (in 5 pati
to be controlled for in comparing immunoprophylactic approaches. At present, DNA polymerase activity or HBV DNA is useful for estimating the level of exposure. In an editorial in this issue, Dr. Dienstag pointed out difficulties in comparing the results of two immunoprophylactic regimens conducted a