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Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-β peptide (1–42)

✍ Scribed by Zhenxia Qin; Zhongwei Sun; Jing Huang; Yinghe Hu; Zirong Wu; Bing Mei


Book ID
116770777
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
457 KB
Volume
444
Category
Article
ISSN
0304-3940

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## Abstract Glucagon‐like peptide‐1(7–36)‐amide (GLP‐1) is an endogenous insulinotropic peptide that is secreted from the gastrointestinal tract in response to food. It enhances pancreatic islet β‐cell proliferation and glucose‐dependent insulin secretion and lowers blood glucose and food intake in