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Mutants of Saccharomyces cerevisiae deficient in adenine phosphoribosyltransferase

โœ Scribed by Amrik Sahota; Prabhakar K. Ranjekar; Juan Alfonzo; Alfred S. Lewin; Milton W. Taylor

Book ID
113193137
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
514 KB
Volume
180
Category
Article
ISSN
0027-5107

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Yeast mutants lacking activity of the enzyme hypoxanthine:guanine phosphoribosyltransferase (H:G-PRT) have been isolated by selecting for resistance to 8-azaguanine in a strain carrying the wild type allele, ade4%, of the gene coding for amidophosphoribosyltransferase (PRPPAT), the first enzyme of d