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Mutants of human insulin-like growth factor I with reduced affinity for the type 1 insulin-like growth factor receptor

✍ Scribed by Cascieri, Margaret A.; Chicchi, Gary G.; Applebaum, Joy; Hayes, Nancy S.; Green, Barbara G.; Bayne, Marvin L.


Book ID
126032717
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
651 KB
Volume
27
Category
Article
ISSN
0006-2960

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Insulin-like growth factor I1 is believed to play an important role in fetal growth and development. The insulin-like growth factor I1 gene expression is tissue specific and developmentally regulated. We have previously shown an enhanced level of insulin-like growth factor I1 messenger RNA and prote