Adenine-requiring mutant strains of S. pombe enter the stationary phase after depleting a culture medium of adenine or its analogues. Stationary phase cells of six mutants defective at different stages of the purine nucleotide synthetic pathway were examined for cell volume and DNA content, and then
Mutants altered in the control co-ordinating cell division with cell growth in the fission yeastSchizosaccharomyces pombe
โ Scribed by Pierre Thuriaux; Paul Nurse; Bruce Carter
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 565 KB
- Volume
- 161
- Category
- Article
- ISSN
- 1617-4615
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โฆ Synopsis
The control co-ordinating cell division with cell growth has been investigated in the fission yeast Schizosaccharomyces pombe. Twenty-five mutants altered in this control have been isolated which have the same growth rate as wild type but divide at a smaller cell size. The mutants define two genes wee 1 and wee 2, both of which are involved in a control initiating mitosis when the cell attains a critical size.
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