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Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels

โœ Scribed by Matthew C. Zimmerman; Larry W. Oberley; Shawn W. Flanagan


Book ID
111180140
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
840 KB
Volume
102
Category
Article
ISSN
0022-3042

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## Abstract A reliable method to induce neural progenitor/stem cells (NPCs) into dopaminergic (DAergic) neurons has not yet been established. As well, the mechanism involved remains to be elucidated. To induce DAergic differentiation from NPCs, a cytokine mixture (Cโ€Mix) of interleukin (IL)โ€1ฮฒ, ILโ€