Mutational analysis of Bax and Bcl-2 in
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Gajja S. Salomons; Corine K. M. Buitenhuis; Cristina MartΓnez MuΓ±oz; Manon Verwi
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Article
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1998
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John Wiley and Sons
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French
β 115 KB
In childhood acute lymphoblastic leukaemia there are large interpatient variations in levels of the apoptosis-regulating proteins Bax and Bcl-2, but the molecular basis for this variation is unknown. Point-mutations in bax have been reported in cell lines derived from haematological malignancies. Fr