Mutant mouse models of oxidative stress
β Scribed by Laurent Pouyet; Alice Carrier
- Book ID
- 106550578
- Publisher
- Springer Netherlands
- Year
- 2009
- Tongue
- English
- Weight
- 239 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0962-8819
No coin nor oath required. For personal study only.
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## Abstract Oxidative stress in the olfactory system is a major factor associated with ageβrelated olfactory impairment, although the mechanisms by which this occurs are not completely understood. The Harlequin mutant mouse (Hq/Y), which carries an Xβlinked recessive mutation in the __Aifm1__ gene,
## Abstract Oxidative stress has been implicated in the pathogenesis of numerous human diseases and disorders, but the mechanistic basis often remains enigmatic. The __Sod2__ mutant mouse, which is sensitized to mitochondrial stress, is an ideal mutant model for studying the role of oxidative stres