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Mutant Genesnm2-1ts, conferring thermoconditional mutagen sensitivity inSaccharomyces cerevisiae, is allelic withRAD5

✍ Scribed by Wolfram Siedel; Martin Brendel


Publisher
Springer-Verlag
Year
1982
Tongue
English
Weight
217 KB
Volume
5
Category
Article
ISSN
0172-8083

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✦ Synopsis


Of two mutant genes (snml-2 ts and snm2-1 ts) conferring thermoconditional mutagen sensitivity in Saccharornyces cerevisiae one (snm2-I ts) is shown to be centromere-linked. At the restrictive temperature this allele reduces UV-induced back mutation frequency of the ochre allele his5-2 but has no influence on forward mutation at the CAN1 locus. Complementation tests and recombination analysis revealed snm2 ts to be alMic with rad5 (rev2).