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Mutant cell lines resistant to azetidine carboxylic acid: Quantitative and qualitative differences in pyrroline-5-carboxylate synthase activity

โœ Scribed by R.J. Smith; R.F. Lodato; D.L. Valle; A. Kazakis

Book ID
118315581
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
360 KB
Volume
99
Category
Article
ISSN
0006-291X

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๐Ÿ“œ SIMILAR VOLUMES

Mutant cell lines resistant to azetidine
Mutant cell lines resistant to azetidine-2-carboxylic acid: Alterations in the synthesis of proline from glutamic acid
โœ Ronna F. Lodato; Robert J. Smith; David L. Valle; Kathleen Crane ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 674 KB

Two mutant Chinese hamster lung fibroblast lines have been isolated that are resistant to the the toxic proline analog L-azetidine-2-carboxylic acid. The line designated AZCA-1 has 30-fold elevated activity of pyrroline-5-carboxylate synthase and a large increase in the rate of proline production an