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Mutagenicity of vinblastine and vincristine in mice

✍ Scribed by N. Savković; J. Pečevski; D. Radivojević; Lj. Vuksanović; E. Djuričić


Book ID
113250168
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
68 KB
Volume
85
Category
Article
ISSN
0165-1161

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The pharmacokinetics of vincristine, vindesine, and vinblastine following IV bolus doses of 0.05 rag, 0.10 rag, and 0.20 mg/kg body weight, respectively, were studied in adult male rhesus monkeys. The alkaloid concentrations were determined by a sensitive radioimmunoassay. Pharmacokinetic data were