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Mutagenicity of derivatives and metabolites of 1-nitropyrene: activation by rat liver S9 and bacterial enzymes

✍ Scribed by Louise M. Ball; Michael J. Kohan; Larry D. Claxton; Joellen Lewtas

Book ID
119092640
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
853 KB
Volume
138
Category
Article
ISSN
0165-1218

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## Abstract Reductive activation of nitroaromatic compounds by bacterial enzymes contributes to the direct‐acting mutagenicity of diesel particle extracts in the __Salmonella__ mutation assay. In this study, the ability of mammalian enzymes to activate diesel particle extract was investigated with