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Mutagenic exploration of the active site of lactate dehydrogenase from Plasmodium falciparum

✍ Scribed by Dilek Turgut-Balik; Debbie K. Shoemark; Richard B. Sessions; Kathleen M. Moreton; J. John Holbrook

Book ID
110291974
Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
56 KB
Volume
23
Category
Article
ISSN
0141-5492

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## Abstract Flavocytochrome __b~2~__ or L‐lactate dehydrogenase from yeasts catalyzes the oxidation of L‐lactate at the expense of monoelectronic acceptors such as cytochrome __c__, its physiological partner. When incubated in the presence of both L‐lactate and a keto acid, the enzyme catalyzes a t