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Mutagenic DNA Repair in Streptomyces

โœ Scribed by Jill Stonesiffer and Richard H. Baltz


Book ID
123631677
Publisher
National Academy of Sciences
Year
1985
Tongue
English
Weight
623 KB
Volume
82
Category
Article
ISSN
0027-8424

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The photoreversibility of UV-induced mutations to Trp+ in strain Escherichia coli WP2 uvrA trp (unable to excise pyrimidine dimers) was lost at different rates during incubation in different media. In Casamino acids medium after a short initial lag, photoreversibility was lost over about one generat

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The polC (= dnaE) temperature-sensitive DNA polymerase III mutation from Escherichia coli BT1026 has been transduced into E. coli WP2 (to give CM731) and WP2 uvr A (to give CM741). In excision-deficient CM741 UV-induced Trp+ mutations progressively lost their photoreversibility during post-irradiati