Mutagenic activity of various kinds of cheese on the Ames, rec and umu assays
β Scribed by Tsutomu Yamaguchi
- Book ID
- 119093281
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 714 KB
- Volume
- 224
- Category
- Article
- ISSN
- 0165-1218
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## Abstract A rapid, highβthroughput bacterial mutagenicity test system has been developed (MutaGen test) that detects reversions of inactivating baseβpair substitutions and frameshifts in a TEMβ1 class A Ξ²βlactamase (ampicillinase) gene. To quickly and sensitively detect mutagens, the system utili
1,3-, 1,6-, and of 1,3-and 1,6-DNP, but not 1,8-DNP, was signifi-1,8-DNP) are direct-acting mutagens in that they do cantly (P Γ΅ 0.05) increased in the Ames assay while not require an exogenous source of enzymes for the mutagenicity of the three DNPs was increased activation to mutagens in the Ames