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Mutagenesis of the bovSERPINA3-3 demonstrates the requirement of aspartate-371 for intermolecular interaction and formation of dimers

✍ Scribed by X. Blanchet; A. Péré-Brissaud; N. Duprat; E. Pinault; D. Delourme; A. Ouali; C. Combet; A. Maftah; P. Pélissier; L. Brémaud


Book ID
112178447
Publisher
Cold Spring Harbor Laboratory Press
Year
2012
Tongue
English
Weight
402 KB
Volume
21
Category
Article
ISSN
0961-8368

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## Abstract The first regulatory step in the synthesis of aromatic amino acids is catalyzed by 3‐deoxy‐D‐arabino‐heptulosonate 7‐phosphate synthase (DAHPS). In Escherichia coli, the allosteric DAHPS exists as three isozymes, AroG, AroF and AroH, each independently feedback‐inhibited by correspondin