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Mutagenesis of murine granulocyte/macrophage-colony-stimulating factor reveals critical residues near the N terminus

โœ Scribed by Nicholas M. GOUGH; Dianne GRAIL; David P. GEARING; Donald METCALF


Book ID
115125436
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
625 KB
Volume
169
Category
Article
ISSN
1432-1327

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We studied the effects of murine recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) on murine hemopoiesis in methylcellulose culture. The GM-CSF was purified from cultures of Saccharomyces cerevisiae transfected with a cloned murine GM-CSF cDNA. In cultures of spleen cells from no