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Mutagen formation in nitration of azo- and oxaarenes

โœ Scribed by Y. Sasaki; K. Ohyama; R. Endo; S. Izumikawa


Book ID
113251577
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
84 KB
Volume
203
Category
Article
ISSN
0165-1161

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A browning model system, consisting of diacetyl and ammonia, produced frameshift and base-pair substitution mutagens when the system was heated over 20 min and 120 min, respectively. The major product was 2,4,5- trimethylimidazole , which showed no mutagenicity toward Salmonella typhimurium strains