✦ LIBER ✦

Muscle-Directed Anti-Aβ Single-Chain Antibody Delivery via AAV1 Reduces Cerebral Aβ Load in an Alzheimer’s Disease Mouse Model

✍ Scribed by Junling Yang, Abhinandan Pattanayak, Min Song, Jinghong Kou, Hiroaki Taguchi, Sudhir Paul, Selvarangan Ponnazhagan, Robert Lalonde, Ken-ichiro Fukuchi

Book ID: 118821380
Publisher: Humana Press Inc
Year: 2012
Tongue: English
Weight: 629 KB
Volume: 49
Category: Article
ISSN: 0895-8696
DOI: 10.1007/s12031-012-9877-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression of anti-Aβ single-chain antib

Expression of anti-Aβ single-chain antibody in skeletal muscle reduces Aβ accumulation in an Alzheimer's disease mouse model

✍ Junling Yang; Abhinandan Pattanayak; Min Song; Jinghong Kou; Hiroaki Taguchi; Su 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 162 KB

Nasal inoculation of an adenovirus vecto

Nasal inoculation of an adenovirus vector encoding 11 tandem repeats of Aβ1-6 upregulates IL-10 expression and reduces amyloid load in a Mo/Hu APPswe PS1dE9 mouse model of Alzheimer's disease

✍ Hong-Duck Kim; Kazuki Tahara; J. Adam Maxwell; Robert Lalonde; Tatsuya Fukuiwa; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 394 KB

Background One of the pathological hallmarks of Alzheimer's disease (AD) is deposits of amyloid β-peptide (Aβ) in neuritic plaques and cerebral vessels. Immunization of AD mouse models with Aβ reduces Aβ deposits and improves memory and learning deficits. Because recent clinical trials of immunizati