Muscarinic regulation of cyclic AMP metabolism in rat neostriatal cultures
β Scribed by Katsunori Nishi; Paul T. Atkins; D. James Surmeier; S.T. Kitai
- Book ID
- 115800249
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 614 KB
- Volume
- 534
- Category
- Article
- ISSN
- 0006-8993
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The regulation of intracellular cyclic AMP (CAMP) formation by adenosine (Ado) and its analogues has been examined in primary cultures of rat-brain astrocytes and neurons. In the presence of the phosphodiesterase inhibitor, Ro 20-1724, basal levels of cAMP ranged from 40-120 pmoVmg protein in both c
## Abstract Evidence is presented that cyclic AMP is engaged in the regulation of a bistability in the glucose and energy metabolism of NH~3~βlimited chemostat cultures of __Escherichia coli__ ML 30. Cyclic AMP probably reverses the repression of the citric acid cycle by glucose favouring the state