Muscarinic receptor subtypes in human and rabbit bladder
โ Scribed by Dr. Michael R. Ruggieri; Donald C. Bode; Robert M. Levin; Alan J. Wein
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 615 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0733-2467
No coin nor oath required. For personal study only.
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SUMMARY: The effects of various muscarinic antagonists on acetylcholine (ACh)-induced pulmonary oedema were studied in isolated perfused rabbit lungs. ACh induced a dose-dependent increase in the capillary filtration coefficient \((\mathbf{K}, \mathbf{c})\). This effect has been previously related t
In the rabbit bladder, pregnancy and prolonged bladder contractions decrease both muscarinic receptor density and contractile response, whereas newborns show enhanced muscarinic contractile response. Although the M 2 receptor predominates in rabbit bladder, we and others have shown that the affinity