Muscarinic cholinergic binding sites in an orthopteran central nervous system

✍ Scribed by Meyer, Mark R. ;Edwards, John S.

• Publisher: John Wiley and Sons
• Year: 1980
• Tongue: English
• Weight: 257 KB
• Volume: 11
• Category: Article
• ISSN: 0022-3034
• DOI: 10.1002/neu.480110207

✦ Synopsis

Abstract

Homogenates of cricket (Acheta domesticus) central nervous system (CNS) specifically bind the potent muscarinic ligand [^3^H]‐QNB. Binding assay and pharmacologic data indicate that the cricket CNS contains a high density of muscarinic cholinergic binding sites. These sites appear to be a unique class of invertebrate cholinergic receptor with properties distinct from those of previously described nicotinic receptors.