Muscarinic acetylcholine receptors involved in the regulation of neural stem cell proliferation and differentiation in vitro
β Scribed by Chang Zhou; Zhe-xing Wen; Dong-mei Shi; Zuo-ping Xie
- Book ID
- 108084370
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 397 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1065-6995
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Binding experiments with the specific muscarinic ligand [ 3 H]N-methylscopolamine ( 3 H-NMS) have shown the presence of constitutive muscarinic acetylcholine receptors (mAChR) on Friend murine erythroleukemia cells (MELC). Competition experiments with a panel of specific antagonists indicated that t
## Abstract In longβterm marrow cultures haemopoiesis can be maintained in vitro for up to 6 months. Critical analysis of the cell populations produced has shown that the stem cells and their committed progeny have characteristics in common with the corresponding cell types in vivo. The maintenance