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Murrayafoline A attenuates the Wnt/β-catenin pathway by promoting the degradation of intracellular β-catenin proteins

✍ Scribed by Hyuk Choi; Jungsug Gwak; Munju Cho; Min-Jung Ryu; Jee-Hyun Lee; Sang Kyum Kim; Young Ho Kim; Gye Won Lee; Mi-Young Yun; Nguyen Manh Cuong; Jae-Gook Shin; Gyu-Yong Song; Sangtaek Oh


Book ID
116299567
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
471 KB
Volume
391
Category
Article
ISSN
0006-291X

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## Abstract Artesunate (ART), a remarkable antimalarial agent, also inhibited the growth of human colorectal carcinoma. As determined by MTT assay, flow cytometry analysis on apoptosis and indirect immunofluorescence analysis on the proliferation‐associated marker Ki67, ART suppressed the prolifera