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Murine CD8+ T cells that specifically delete autologous CD4+ T cells expressing Vβ8 TCR: a role of the Qa-1 molecule

✍ Scribed by Hong Jiang; Randle Ware; Alan Stall; Lorraine Flaherty; Leonard Chess; Benvenuto Pernis


Book ID
117723558
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
1010 KB
Volume
2
Category
Article
ISSN
1074-7613

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## Abstract Using a primary limiting dilution approach to generate T cell lines, we compared myelin basic protein (MBP)‐specific T cell clones from naive unprimed Lewis rat thymuses with the corresponding T cell repertoire of primed rats. We found that in the naive thymus repertoire MBP‐specific, e