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Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

✍ Scribed by David A van Heel; Subrata Ghosh; Matt Butler; Karen A Hunt; Anna MC Lundberg; Tariq Ahmad; Dermot PB McGovern; Clive Onnie; Kenichi Negoro; Sue Goldthorpe; Brian MJ Foxwell; Christopher G Mathew; Alastair Forbes; Derek P Jewell; Raymond J Playford


Book ID
117289517
Publisher
The Lancet
Year
2005
Tongue
English
Weight
155 KB
Volume
365
Category
Article
ISSN
0140-6736

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## Background: Mutations in the gene encoding the nucleotide-binding oligomerization domain 2 (nod2) protein are associated with crohn's disease (cd), but the mechanism underlying this is not completely understood. to study the mechanism of cd resulting from nod2 mutations, we analyzed nod2-depende